Fatigued all the time

One of the most common causes of fatigue is iron deficiency. Indeed, it’s the most common nutrient deficiency worldwide. Iron is a mineral that plays an essential role in the body.
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How pathology testing can help identify the cause of patient fatigue ?
Fatigue is a symptom which can have debilitating effects on patients, posing a negative impact on their overall quality of life including work, family life and general social relationships. Patients experiencing chronic, ongoing fatigue often find it difficult to convey their symptoms to their healthcare..
fatgued all the time test

What About Anemia?

One of the most common conditions associated with fatigue, is anaemia. Anaemia can be caused by a reduced number of red blood cells or impaired haemoglobin production, which is responsible for transporting oxygen in peripheral blood.As the levels of haemoglobin drop, the ability of the blood to deliver oxygen to organs, muscles and tissues declines. This means that less energy is available to these organs resulting in symptoms perceived as fatigue.

Full Blood Count

Mean Cell Hemoglobin
Mean Cell Hemoglobin
Concentration (MCHC)
Red Blood Cell Mean
Cell Volume (MCV)
Red Blood Cell Count
Basophil Count
Lymphocyte Count
Eosinophil Count
Monocyte Count
Neutrophil Count
White Blood Cell Count
Platelet Count Diabetes Health

Kidney Health

Cystatin C

Nutritional Health

Calcium (Adjusted)
Folic Acid
Vitamin B12
Vitamin D

Thyroid Health

Thyroid Stimulating
Free Thyroxine FT3
Free Tri-iodothyronine (FT4)
Anti-Thyroglobulin Antibody
Anti-Thyroid Peroxidase
Antibody (Anti-TPO)

Diabetes Health

Glucose *
Infection & Inflammation
C-Reactive Protein (CRP)

Iron Status

Transferrin Saturation

Health Tips & Info

Additionally, children’s reference ranges are designed to provide more accurate pediatric nutritional evaluations. Identifying metabolic blocks that can be treated nutritionally allows individual tailoring of interventions that maximize patient responses and lead to improved patient outcomes.
Fatigue is a common symptom of thyroid disease. The adrenal and the thyroid systems are closely involved with direct cross regulation between the hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pituitary-thyroid (HPT) axis. Increased stress can cause a reduction in the production of thyroid hormones. Glucocorticoids can inhibit conversion of T4 to T3 resulting in a reduction of serum T3 levels. Studies have also confirmed that prolonged stress can cause a decrease in peripheral thyroid hormone levels.
Thyroid hormone is required in several energy producing processes, namely, the Creb’s citric acid cycle and in oxidative phosphorylation. A thyroid problem can in fact have a direct impact on ATP producing mechanisms thereby resulting in fatigue.
Low levels of vitamin D have been seen in patients presenting with fatigue. More so, it has been found that normalization of low vitamin D levels in patients with fatigue significantly improves symptoms.

There are a number of mechanisms by which vitamin D is believed to ameliorate symptoms of fatigue. Vitamin D is involved in the process of energy production in the body. Research has shown that low levels of vitamin D are associated with suboptimal mitochondrial function and therefore reduced energy levels. Mitochondria are part of the cell involved in ATP production, the body’s main energy production mechanism.

Vitamin D is also required for calcium homeostasis, supporting bone density and turnover. A deficiency in Vitamin D results in skeletal demineralisation and muscle weakness. Fatigue is believed to be the end result of the underlying muscle fatigue, which is more commonly encountered than muscle weakness.
Additionally, Vitamin D is also involved in supporting immune function by down regulating cytokine, T helper cell and NF-κB activation, therefore reducing pro-inflammatory immune responses, and enhancing immune function

Melatonin dysregulation

A common complaint of patients with fatigue is sleep impairment. The hormone melatonin is significant in the regulation of the circadian rhythm, regulating the sleep-wake cycle. Ideally in humans melatonin levels should start to increase with the onset of darkness, and reduce again during the second half of the night.
Saliva Melatonin Testing
Gastrointestinal Tract
Testing for MTHFR
Adrenal Hormone
Vitamin D deficiency

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